Elabscience

Recombinant Human BCL2L1/Bcl-XL Protein (His Tag)

Product Code:
 
PKSH033757
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSH033757-10ug10ug£297.00
Quantity:
PKSH033757-50ug50ug£498.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
BCL2L1;Bcl-XL
Accession:
Q07817
Background:
Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.
Calculated MW:
24.85 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 20mM HEPES, 50mM KCl, 20% Glycerol, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
29 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met1-Arg212
Target Synonym:
Bcl-2-Like Protein 1;Bcl2-L-1;Apoptosis Regulator Bcl-X;Bcl-X;bcl-xL;BCL-XL/S;bcl-xS;BCL2L;BCLX;BCLXL;BCLXS;PPP1R52
UNIProt ID:
Q07817

Documents