Elabscience

Recombinant Human GM2A Protein (Human Cells, His Tag)

Product Code:
 
PKSH033306
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033306-10ug10ug£219.00
Quantity:
PKSH033306-50ug50ug£497.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
GM2A
Accession:
P17900
Background:
Ganglioside GM2 activator (GM2A) is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A (HEXB). HEXB together with GM2A, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. GM2A accommodate several single chain phospholipids and fatty acids, is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Calculated MW:
18.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl,150mM NaCl,pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
20 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser32-Ile193
Target Synonym:
Ganglioside GM2 activator;Cerebroside sulfate activator protein;GM2-AP;Sphingolipid activator protein 3;SAP-3
UNIProt ID:
P17900

Documents