Elabscience

Recombinant Human SMPDL3A Protein (His Tag)

Product Code:
 
PKSH033291
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033291-10ug10ug£219.00
Quantity:
PKSH033291-50ug50ug£497.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
SMPDL3A
Accession:
Q92484
Background:
Acid sphingomyelinase-like phosphodiesterase 3a (SMPDL3A ) is a novel liver X receptor (LXR) -regulated gene; with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR function as physiological sensors of cholesterol metabolites (oxysterols); regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems; revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases.
Calculated MW:
49.9 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
59 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu23-Tyr453
Target Synonym:
Acid Sphingomyelinase-Like Phosphodiesterase 3a;ASM-Like Phosphodiesterase 3a;SMPDL3A;ASML3A
UNIProt ID:
Q92484

Documents