Elabscience

NUDT15 Polyclonal Antibody

Product Code:
 
E-AB-64940
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Rat spleen using NUDT15 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of Rat spleen using NUDT15 Polyclonal Antibody at dilution of 1:1000.

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E-AB-64940-60uL60uL£210.00
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E-AB-64940-120uL120uL£291.00
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E-AB-64940-200uL200uL£431.00
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Further Information

Abbreviation:
NUDT15
Background:
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
18kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human NUDT15 (NP_060753.1).
ObservedMW:
19kDa
Purification method:
Affinity purification
Target Synonym:
NUDT15;MTH2;NUDT15D
UNIProt ID:
Q9NV35

Documents