Elabscience

ELANE Polyclonal Antibody

Product Code:
 
E-AB-64417
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using ELANE Polyclonal Antibody at dilution of 1:3000.
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Western blot analysis of extracts of various cell lines using ELANE Polyclonal Antibody at dilution of 1:3000.

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CodeSizePrice
E-AB-64417-60uL60uL£210.00
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E-AB-64417-120uL120uL£291.00
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E-AB-64417-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
ELANE
Background:
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
28kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ELANE (NP_001963.1).
ObservedMW:
29kDa
Purification method:
Affinity purification
Target Synonym:
ELANE;ELA2;GE;HLE;HNE;NE;PMN-E;SCN1
UNIProt ID:
P08246

Documents