Elabscience

(KO Validated) CBX3 Polyclonal Antibody

Product Code:
 
E-AB-62382
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 2
Western blot analysis of extracts from normal (control) and CBX3 knockout (KO) HeLa cells using CBX3 Polyclonal Antibody at dilution of 1:500.
2 / 2
Immunofluorescence analysis of U-2 OS cells using CBX3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
❮❯

Western blot analysis of extracts from normal (control) and CBX3 knockout (KO) HeLa cells using CBX3 Polyclonal Antibody at dilution of 1:500.
Immunofluorescence analysis of U-2 OS cells using CBX3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-62382-60uL60uL£224.00
Quantity:
E-AB-62382-120uL120uL£317.00
Quantity:
E-AB-62382-200uL200uL£465.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
CBX3
Background:
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
20kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human CBX3 (NP_009207.2).
ObservedMW:
23kDa
Purification method:
Affinity purification
Target Synonym:
CBX3;HECH;HP1-GAMMA;HP1Hs-gamma
UNIProt ID:
Q13185

Documents