Elabscience

Catenin beta Polyclonal Antibody

Product Code:
 
E-AB-70005
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry analysis of paraffin-embedded Human colon tissue using Catenin beta Polyclonal Antibody at dilution of 1:300.
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Immunohistochemistry analysis of paraffin-embedded Human Colon using Catenin beta Polyclonal Antibody(Elabscience Product Detected by Lifespan).
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Immunohistochemistry analysis of paraffin-embedded Human colon tissue using Catenin beta Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Human Colon using Catenin beta Polyclonal Antibody(Elabscience Product Detected by Lifespan).

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E-AB-70005-60uL60uL£184.00
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E-AB-70005-120uL120uL£251.00
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E-AB-70005-200uL200uL£351.00
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This product comes from: China.
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  • Further Information
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Further Information

Abbreviation:
Catenin beta
Background:
CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
92kDa
Concentration:
0.97 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:300-1:1000, IF 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse β-catenin
ObservedMW:
92kDa
Purification method:
Affinity purification
Target Synonym:
Beta catenin;Beta-catenin;Cadherin associated protein;Catenin (cadherin associated protein);beta 1;88kDa;Catenin beta 1;Catenin beta-1;CATNB;CHBCAT;CTNB1;CTNNB;CTNNB1;DKFZp686D02253;FLJ25606;FLJ37923;OTTHUMP00000162082;OTTHUMP00000165222;OTTHUMP00000165223;OTTHUMP00000209288;OTTHUMP00000209289
UNIProt ID:
P35222,Q02248,Q9WU82

Documents

References

  • https://academic.oup.com/bbb/article-abstract/85/11/2263/6366227