Recombinant Mouse TSLP Receptor/CRLF2 Protein (His Tag)

TSLP Receptor;CRLF2

Q8CII9

The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common γ receptor?like chain (TSLPR-γ) and a common interleukin 7 (IL-7) Rα chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7Rα chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells.

23.7 kDa

< 1.0 EU per ug of the protein as determined by the LAL method.

HEK293 Cells

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

C-6His

35-40 kDa

> 95 % as determined by reducing SDS-PAGE.

Ala20-Leu233

CRL2;CRLF2;CRL2 cytokine receptor;Cytokine receptor-like 2;cytokine receptor-like factor 2;ILXR;IL-XR;P2RY8/CRLF2 fusion;Thymic stromal lymphopoietin protein receptor;Thymic stromal-derived lymphopoietin receptor;TSLP receptor;TSLPR

Q8CII9