Elabscience

Recombinant Mouse FcRn & B2M Heterodimer Protein (His Tag)

Product Code:
 
PKSM041017
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSM041017-10ug10ug£150.00
Quantity:
PKSM041017-50ug50ug£248.00
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This product comes from: China.
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Further Information

Abbreviation:
FcRn & B2M Heterodimer
Accession:
Q61559&P01887
Background:
FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51 (alpha chain) and Beta-2-microglobulin (Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).
Calculated MW:
44.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
42-58 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser22-Val301&Ile21-Met119
Target Synonym:
IgG receptor FcRn;Neonatal Fc receptor;FCRN
UNIProt ID:
Q61559&P01887

Documents