Elabscience

Recombinant Human FKBP3/FKBP25 Protein (His Tag)

Product Code:
 
PKSH032876
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped at ambient temperature. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Lyophilized protein should be stored at < -20°C though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
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CodeSizePrice
PKSH032876-10ug10ug£244.00
Quantity:
PKSH032876-50ug50ug£297.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
FKBP3;FKBP25
Accession:
Q00688
Background:
FKBP25 contains 1 PPIase FKBP-type domain; belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin; as well as histone deacetylases; the transcription factor YY1; casein kinase II; and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Calculated MW:
27.3 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 1mM DTT, 10% glycerol .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-6His
ObservedMW:
30 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Asp224
Target Synonym:
Peptidyl-prolyl cis-trans isomerase FKBP3;PPIase FKBP3;25 kDa FK506-binding protein;25 kDa FKBP;FKBP-25;FK506-binding protein 3;FKBP-3;Immunophilin FKBP25;Rapamycin-selective 25 kDa immunophilin;Rotamase;FKBP25
UNIProt ID:
Q00688

Documents