Elabscience

Recombinant Human Carbonic Anhydrase 8/CA8 Protein (His Tag)(Active)

Product Code:
 
PKSH032165
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped on dry ice/blue ice. Upon receipt store it immediately at the storage temperature listed.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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CodeSizePrice
PKSH032165-10ug10ug£534.00
Quantity:
PKSH032165-50ug50ug£649.00
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Further Information

Abbreviation:
Carbonic Anhydrase 8;CA8
Accession:
P35219
Activity:
Measured by its esterase activity The specific activity is 162. 5 pmol/min/ug.
Background:
Carbonic Anhydrase 8 (CA8) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Because CA8 has some sequence similarity with other known carbonic anhydrase genes, it was firstly called as CA-related protein. Nevertheless, CA8 does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3), which is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.
Calculated MW:
34.0 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 500mM NaCl, 1mM DTT, pH 8.5 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
40 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala2-Gln290
Target Synonym:
Carbonic Anhydrase-Related Protein;CARP;Carbonic Anhydrase VIII;CA-VIII;CA8;CALS;CAMRQ3;MGC120502;MGC99509
UNIProt ID:
P35219

Documents