Elabscience

PILRA Polyclonal Antibody

Product Code:
 
E-AB-91758
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using PILRA Polyclonal Antibody at1:1000 dilution.
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Western blot analysis of extracts of various cell lines using PILRA Polyclonal Antibody at1:1000 dilution.

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CodeSizePrice
E-AB-91758-60uL60uL£210.00
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E-AB-91758-120uL120uL£291.00
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E-AB-91758-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
PILRA
Background:
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
34kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human PILRA
ObservedMW:
45kDa
Purification method:
Affinity purification
Target Synonym:
PILRA;FDF03
UNIProt ID:
Q9UKJ1

Documents