Elabscience

HEXA Polyclonal Antibody

Product Code:
 
E-AB-92661
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using HEXA Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using HEXA Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-92661-60uL60uL£210.00
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E-AB-92661-120uL120uL£291.00
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E-AB-92661-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
HEXA
Background:
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
19kDa/60kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human HEXA
ObservedMW:
55KDa
Purification method:
Affinity purification
Target Synonym:
HEXA;TSD
UNIProt ID:
P06865

Documents