Elabscience

MASP1 Polyclonal Antibody

Product Code:
 
E-AB-92666
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of HeLa cells using MASP1 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of HeLa cells using MASP1 Polyclonal Antibody at 1:1000 dilution.

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E-AB-92666-60uL60uL£210.00
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E-AB-92666-200uL200uL£431.00
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Further Information

Abbreviation:
MASP1
Background:
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
43kDa/68kDa/79kDa/81kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human MASP1
ObservedMW:
60kDa
Purification method:
Affinity purification
Target Synonym:
MASP1;3MC1;CRARF;CRARF1;MAP1;MASP;MASP3;MAp44;PRSS5;RaRF
UNIProt ID:
P48740

Documents