Elabscience

LPCAT3 Polyclonal Antibody

Product Code:
 
E-AB-93213
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of various lysates using LPCAT3 Polyclonal Antibody at 1:500 dilution.
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Western blot analysis of various lysates using LPCAT3 Polyclonal Antibody at 1:500 dilution.

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E-AB-93213-60uL60uL£210.00
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E-AB-93213-120uL120uL£291.00
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E-AB-93213-200uL200uL£431.00
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Further Information

Abbreviation:
LPCAT3
Background:
Lysophospholipid O-acyltransferase (LPLAT that catalyzes the reacylation step of the phospholipid remodeling process also known as the Lands cycle. Catalyzes transfer of the fatty acyl chain from fatty acyl-CoA to 1-acyl lysophospholipid to form various classes of phospholipids. Converts 1-acyl lysophosphatidylcholine (LPC into phosphatidylcholine (PC (LPCAT activity, 1-acyl lysophosphatidylserine (LPS into phosphatidylserine (PS (LPSAT activity and 1-acyl lysophosphatidylethanolamine (LPE into phosphatidylethanolamine (PE (LPEAT activity. Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Has higher activity for LPC acyl acceptors compared to LPEs and LPSs. Can also transfer the fatty acyl chain from fatty acyl-CoA to 1-O-alkyl lysophospholipid or 1-O-alkenyl lysophospholipid with lower efficiency (By similarity. Acts as a major LPC O-acyltransferase in liver and intestine. As a component of the liver X receptor/NR1H3 or NR1H2 signaling pathway, mainly catalyzes the incorporation of arachidonate into PCs of endoplasmic reticulum (ER membranes, increasing membrane dynamics and enabling triacylglycerols transfer to nascent very low-density lipoprotein (VLDL particles.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human LPCAT3
ObservedMW:
56KDa
Purification method:
Affinity purification
Target Synonym:
C3F;LPCAT;LPLAT 5;LPSAT;MBOAT5;OACT5;nessy;LPCAT3
UNIProt ID:
Q6P1A2

Documents