Elabscience

Recombinant Human SOCS2 protein (His tag)

Product Code:
 
PDEH100325
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PDEH100325-20ug20ug£113.00
Quantity:
PDEH100325-100ug100ug£140.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
SOCS2
Accession:
O14508
Background:
SOCS-2 (Suppressor of cytokine signaling 2; also CIS-2 and SSI-2) is a 25 kDa member of the SOCS family of proteins. It is an SH2-domain containing cytoplasmic adaptor protein expressed by multiple cell types. It blocks receptor signaling by binding to phosphorylated tyrosines in the cytoplasmic domain of select receptors, including the receptors for leptin, IGF-I and GH. Human SOCS-2 is 198 amino acids (aa) in length and contains one SH2 domain (aa 48-156) and a SOCS box (aa 160-198) that mediates interaction with elongin B or C of the E3 ubiquitin ligase complex. There is one splice variant that shows an Arg-rich eight aa substitution for aa 31-39. Full-length SOCS-2 is 94% and 96% aa identical to mouse and porcine SOCS-2, respectively.
Calculated MW:
21.67 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His & C-His
ObservedMW:
25 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Val 198
Target Synonym:
Suppressor of cytokine signaling 2;SOCS2;Cytokine-inducible SH2 protein 2;STAT-induced STAT inhibitor 2
UNIProt ID:
O14508

Documents