Elabscience

Recombinant Human CLEC10A/CD301 Protein (Fc Tag)

Product Code:
 
PKSH031411
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSH031411-50ug50ug£615.00
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This product comes from: China.
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Further Information

Abbreviation:
CLEC10A;CD301
Accession:
Q8IUN9-2
Background:
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
Calculated MW:
54.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-hFc
ObservedMW:
58 kDa
Purity:
> 85 % as determined by reducing SDS-PAGE.
Sequence:
Gln61-His292
Target Synonym:
C-Type Lectin Domain Family 10 Member A;C-Type Lectin Superfamily Member 14;Macrophage Lectin 2;CD301;CLEC10A;CLECSF13;CLECSF14;HML
UNIProt ID:
Q8IUN9

Documents