Diaclone

Mouse Anti-Human CD130 BioActive Antibody, Clone B-K5, Azide free

Product Code:
 
852.070.000
Product Group:
 
Primary Antibodies
Supplier:
 
Diaclone
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
B-K5
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Functional Study
 

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852.070.000200ug/200ul£232.00
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  • Further Information
  • References
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Further Information

Activity:
Inhibits CNTF activity. Inhibits OSM binding to gp130
Antigen:
CD130 / gp130
Antigen Synonyms:
gp130
Biological Acivity:
Inhibits CNTF activity. Inhibits OSM binding to gp130
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Natural soluble gp130
Reactivity:
Human
Research Area:
Cytokine / Chemokine ReceptorsCD Markers
Specificity:
Recognises Gp130 common subunit for IL-6 IL-11 OSM LIF CNTF CT-1 receptors a 130-140 kDa protein
Workshop:
VI

References

  1. Auguste P. et al. J Biol Chem.1997; 272(25): 15760-4.. Signaling of type II oncostatin M receptor. https://www.ncbi.nlm.nih.gov/pubmed/9188471
  2. Avril P. et al. J Bone Oncol.2016?;5(1): 5-14. Mesenchymal stem cells increase proliferation but do not change quiescent state of osteosarcoma cells: Potential implications according to the tumor resection status. https://www.ncbi.nlm.nih.gov/pubmed/26998421
  3. Baumann H. et al. Proc Natl Acad Sci.1996;93(16): 8374-8.. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. https://www.ncbi.nlm.nih.gov/pubmed/8710878
  4. Chevalier S. et al. J Biol Chem.1996; 271(25): 14764-72.. Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein. https://www.ncbi.nlm.nih.gov/pubmed/8662918
  5. Durda P. J. et al. Mol Cancer Res.2003; 1(6): 411-9.. Induction of "antigen silencing" in melanomas by oncostatin M: down-modulation of melanocyte antigen expression. https://www.ncbi.nlm.nih.gov/pubmed/12692260
  6. Gu Z. J. et al. J Immunol Methods1996; 190(1): 21-7.. Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor interleukin-6 interleukin-11 leukemia inhibitory factor or oncostatin M. https://www.ncbi.nlm.nih.gov/pubmed/8601708