TargetMol

γ-2-MSH (41-58), amide

Product Code:
 
TAR-TP1532
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-TP1532-100mg100mgEnquire
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TAR-TP1532-500mg500mgEnquire
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Further Information

Bioactivity:
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line.
CAS:
799841-81-9
Molecular Weight:
1569.79
Purity:
0.98

References

Joseph CG, et al. ??-Melanocyte stimulation hormone (??-MSH) truncation studies results in the cautionary note that ??-MSH is not selective for the mouse MC3R over the mouse MC5R. Peptides. 2010 Dec;31(12):2304-13.