GPX3 (human) (rec.)

Glutathione Peroxidase 3; Plasma Glutathione Peroxidase; Extracellular Glutathione Peroxidase; GPx-3; GSHPx-3; GPx-P; GSHPx-P

0.5mg/ml

32160000

<0.1EU/µg purified protein (LAL test; Lonza).

liquid

Liquid. 0.2µm-filtered solution in PBS, pH7.2.

After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.For maximum product recovery after thawing, centrifuge the vial before opening the cap.

Protein. Human GPX3 (aa 21-226) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Liquid. 0.2µm-filtered solution in PBS, pH7.2. Purity: >90% (SDS-PAGE). Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.

~30kDa (SDS-PAGE)

P22352

Plastic Vial

Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.

>90% (SDS-PAGE)

Human GPX3 (aa 21-226) is fused at the N-terminus to a FLAG®-tag.

HEK 293 cells

FLAG

Non-hazardous

Other Proteins

12352202

Stable for at least 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.