AdipoGen Life Sciences

IL-1 Receptor Type I (human):Fc (human) (rec.) (MultiPack)

Product Code:
 
AG-40B-0024
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Blue Ice
Storage:
 
-20°C
 

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CodeSizePrice
AG-40B-0024-C05050 ug£230.00
Quantity:
AG-40B-0024-30503 x 50 ug£450.00
Quantity:
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Further Information

Alternate Names/Synonyms:
IL-1 Receptor Type I; Interleukin-1 Receptor Type I; RI; Interleukin-1 Receptor alpha CD121a; CD121 Antigen-like Family Member A
Biological Activity:
Blocks IL-1beta activity.
Concentration:
1mg/ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.1EU/µg purified protein (LAL test; Lonza).
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human IL-1beta. Purity: >95% (SDS-PAGE). IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
Molecular Weight:
~80kDa (SDS-PAGE)
NCBI, Uniprot Number:
P14778
Package Type:
Plastic Vial
Product Description:
IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
Purity:
>95% (SDS-PAGE)
Sequence:
Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.
Source / Host:
HEK 293 cells
Specificity:
Binds to human IL-1beta.
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Interleukins
UNSPSC Number:
41116127
Use & Stability:
Working aliquots are stable for up to 3 months when stored at -20°C.