Fas (human):Fc (human) (rec.) (MultiPack)

Tumor Necrosis Factor Receptor Superfamily Member 6; TNFRSF6; Apo-1 Antigen; CD95

Blocks the binding of FasL to Fas.

1mg/ml after reconstitution.

32160000

<0.01EU/µg purified protein (LAL test; Lonza).

liquid

Lyophilized. Contains PBS.

After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.

Protein. The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170). Source: HEK 293 cells. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds human and mouse FasL. Purity: >95% (SDS-PAGE). FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.

~47kDa (SDS-PAGE).

P25445

Plastic Vial

FasL is a cytokine that binds to Fas/TNFRSF6, a receptor that transduces the apoptotic signal into cells. FasL is involved in cytotoxic T cell mediated apoptosis and in T cell development.

>95% (SDS-PAGE)

The Fc portion of human IgG1 is fused to the C-terminus of human Fas (aa 26-170).

HEK 293 cells

Binds human FasL with an ED50 of <5ng/ml. Binds mouse FasL.

Fc

Non-hazardous

Other Proteins

12352202

Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.