VEGF 164 (mouse) (rec.)
Product Code:
AG-40T-0044
AG-40T-0044
Regulatory Status:
RUO
RUO
Target Species:
Mouse
Mouse
Shipping:
Blue Ice
Blue Ice
Storage:
+4°C
+4°C
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| AG-40T-0044-C005 | 5 ug | £180.00 |
Quantity:
| AG-40T-0044-C020 | 20 ug | £385.00 |
Quantity:
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
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Further Information
Alternate Names/Synonyms:
Vascular Endothelial Growth Factor; VEGF-A; VPF
Biological Activity:
The ED50 for stimulation of cell proliferation by human umbilical vein endothelial cells for VEGF 164 has been determined to be in the range of 1-5ng/ml.
EClass:
32160000
Form (Short):
liquid
Formulation:
Lyophilized.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.For long term storage we recommend to add at least 0.1% human or bovine serum albumin.
Long Description:
Protein. Mouse VEGF 164 (164aa). Source: Sf9 cells. Lyophilized. Purity: >95% (SDS-PAGE). Mouse vascular endothelial growth factor 164 (VEGF 164) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. It is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo and is also a chemoattractant for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.
Molecular Weight:
~48kDa
NCBI, Uniprot Number:
Q00731
Package Type:
Plastic Vial
Product Description:
Mouse vascular endothelial growth factor 164 (VEGF 164) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. It is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo and is also a chemoattractant for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.
Purity:
>95% (SDS-PAGE)
Sequence:
Mouse VEGF 164 (164aa).
Source / Host:
Sf9 cells
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.
Documents
References
Bevacizumab as a potent inhibitor of inflammatory corneal angiogenesis and lymphangiogenesis: F. Bock, et al.; Invest. Ophthalmol. Vis. Sci. 48 2545 (2007)