AdipoGen Life Sciences

VEGF-C (human) (rec.) (His)

Product Code:
 
AG-40T-0046
Product Group:
 
Recombinant Proteins
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Blue Ice
Storage:
 
+4°C
 

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AG-40T-0046-C02020 ug£295.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Vascular Endothelial Growth Factor C; VRP; Flt4-L
EClass:
32160000
Form (Short):
solid
Formulation:
Lyophilized.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. Human VEGF-C (115aa) is fused at the C-terminus to a His-tag. Source: Sf9 cells. Lyophilized. Purity: >90% (SDS-PAGE). VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
Molecular Weight:
~18-24kDa
NCBI, Uniprot Number:
P49767
Package Type:
Plastic Vial
Product Description:
VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
Purity:
>90% (SDS-PAGE)
Sequence:
Human VEGF-C (115aa) is fused at the C-terminus to a His-tag.
Source / Host:
Sf9 cells
TAGs:
His
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.

References

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis: Y. Wang, et al.; Nature 465, 483 (2010) | Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1: N. Platonova, et al.; Blood 121, 1229 (2013)