Asialo-GM2
Product Code:
AG-CN2-9009
AG-CN2-9009
Regulatory Status:
RUO
RUO
Shipping:
Ambient
Ambient
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| Code | Size | Price |
|---|
| AG-CN2-9009-C100 | 100 ug | £220.00 |
Quantity:
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
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Typical lead time: 7-10 working days.
Contact us for more accurate information.
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Further Information
Alternate Names/Synonyms:
Ceramide trihexoside; Gangliotriosylceramide; Asialoganglioside-GM2
CAS:
35960-33-9
EClass:
32160000
Endotoxin:
Not detectable.
Form (Short):
solid
Formulation:
Lyophilized.
Handling Advice:
Hygroscopic.Protect from moisture.
InChi:
InChI=1S/C56H104N2O18/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-44(64)58-39(40(63)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)37-71-55-50(69)48(67)53(42(35-60)73-55)76-56-51(70)49(68)52(43(36-61)74-56)75-54-45(57-38(3)62)47(66)46(65)41(34-59)72-54/h30,32,39-43,45-56,59-61,63,65-70H,4-29,31,33-37H2,1-3H3,(H,57,62)(H,58,64)/b32-30+/t39-,40+,41?,42?,43?,45?,46-,47?,48?,49?,50?,51?,52-,53+,54+,55+,56-/m0/s1
InChiKey:
FOCMISOLVPZNSV-ZLIWCFRDSA-N
Long Description:
Chemical. CAS: 35960-33-9. Formula: C56H104N2O18. MW: 1093.4 (calculated on sphingosine C18:1 and stearic acid). Semisynthetic. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Asialo-ganglioside GM2 is a major neural ganglioside in Tay Sachs and Sandhoff diseases.
MDL:
MFCD00131129
Molecular Formula:
C56H104N2O18
Molecular Weight:
1093.4 (calculated on sphingosine C18:1 and stearic acid)
Package Type:
Glass Vial
Product Description:
Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Asialo-ganglioside GM2 is a major neural ganglioside in Tay Sachs and Sandhoff diseases.
Purity:
>98% (TLC)
Sequence:
Structure: GgOse3Cer; beta-GalNAc-(1-4)-]beta-Gal-(1-4)-beta-Glc-(1-1)-Cer; Cer: Sphingosine C18:1-C20:1, ~1:1 by vol.; stearic acid over 90%
SMILES:
[H][C@@](CO[C@@H]1O[C@@H](CO)[C@@H](O[C@@H]2OC(CO)[C@H](O[C@H]3O[C@@H](CO)[C@H](O)C(O)C3NC(C)=O)[C@H](O)C2O)C(O)C1O)(NC(=O)CCCCCCCCCCCCCCCCC)[C@]([H])(O)C=CCCCCCCCCCCCCC
Solubility Chemicals:
Soluble in chloroform:methanol (2:1).
Source / Host:
Semisynthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Glycolipids/Phospholipids/Sphingolipids
UNSPSC Number:
12352211
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
Documents
References
Role of membrane gangliosides in the binding and action of bacterial toxins: P.H. Fishman; J. Membr. Biol. 69, 85 (1982)