Further Information
NEU, NGL, HER2, TKR1, CD340, HER-2, MLN19, HER-2/neu, BHLHE39, C-erbB-2, ErbB2
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.
- Dittadi, R. et al. (2000) J. Natl. Cancer Inst. 92, 1443-1444. Muthuswamy, S. K. et al. (1999) Mol. Cell. Biol. 19, 6845-6857. Qian, X. et al. (1994) Proc. Natl. Acad. Sci. USA 91, 1500-1504.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
HER2 (Phospho-Tyr877) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 877 (T-E-Y (p) -H-A) derived from Human HER2.
Phospho-Specific
2064
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
ERBB2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
185 kDa
NP_001005862.1
54792098
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific
This antibody detects endogenous level of HER2 only when phosphorylated at tyrosine 877.
P04626