ProSci

HSD11B2 Antibody

Product Code:
 
PSI-XW-8141
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Chicken
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Monkey
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
HSD11B2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures
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E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

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CodeSizePrice
PSI-XW-8141-0.05mg0.05mg£801.00
Quantity:
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This product comes from: United States.
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Further Information

Additional Names:
HSD11K, Corticosteroid 11-beta-dehydrogenase isozyme 2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, AME, AME1, HSD2, HSD11K, SDR9C3, Corticosteroid 11bdehydrogenase, isozyme 2, 11-beta-HSD2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase
Application Note:
Corticosteroid 11-β-dehydrogenase, isozyme 2 antibody can be used for the detection of Corticosteroid 11-β-dehydrogenase, isozyme 2 by Western Blot.
Background:
FUNCTION: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

DISEASE: Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
181-405
NCBI Gene ID #:
3291
NCBI Official Name:
hydroxysteroid (11-beta) dehydrogenase 2
NCBI Official Symbol:
HSD11B2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44.1 kDa (calculated)
Protein Accession #:
NP_000187.1
Protein GI Number:
4504499
Purification:
Immunoaffinity Purified
Swissprot #:
P80365
User NOte:
Optimal dilutions for each application to be determined by the researcher.