SCARB2 Antibody
| Code | Size | Price |
|---|
| PSI-46-989-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
SCARB2, scavenger receptor class B, member 2, AMRF, CD36L2, HLGP85, LIMPII, 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2, CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II), lysosomal integral membrane protein II
Application Note:
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx. 80kDa band observed in Human Brain (Cortex and Cerebellum) lysates (calculated MW of 54.3kDa according to NP_005497.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Fujita et al, Biochem Biophys Res Commun. 1992 Apr 30;184(2):604-11.; PMID: 1374238). Recommended concentration: 0.1-0.3ug/ml.Immunohistochemistry:In paraffin embedded Human Cerebral Cortex shows lysosomal staining. Recommended concentration, 3-5ug/ml.
Background References:
- Berkovic SF, Dibbens LM, Oshlack A, Silver JD, Katerelos M, Vears DF, L?llmann-Rauch R, Blanz J, Zhang KW, Stankovich J, Kalnins RM, Dowling JP, Andermann E, Andermann F, Faldini E, D'Hooge R, Vadlamudi L, Macdonell RA, Hodgson BL, Bayly MA, Savige J, Mulley JC, Smyth GK, Power DA, Saftig P, Bahlo M. Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis. Am. J. Hum. Genet. 2008 Mar 82 (3): 673-84.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse
Immunogen:
The immunogen for this antibody is: C-NKANIQFGDNGTTIS
NCBI Gene ID #:
950
NCBI Official Name:
scavenger receptor class B, member 2
NCBI Official Symbol:
SCARB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_005497.1
Protein GI Number:
5031631
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Homeostasis
SPECIFICITY:
This antibody is expected to recognize reported isoform 1 (NP_005497.1) only.
Swissprot #:
Q14108