ProSci

TNFRSF7 Recombinant Protein

Product Code:
 
PSI-96-133
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-133-0.2mg0.2mg£626.00
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Further Information

Additional Names:
CD27, TNFRSF7, S152, S152. LPFS2, T14, Tp55
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
Background References:
  • Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.
  • Gravestein L.A., et al., 1998, Eur. J. Immunol. 28:2208-2216.
  • Prasad K.V.S., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD27 protein at 2μg/mL (100μl/well) can bind biotinylated human CD70 with a linear range of 0. 25 - 16 ng/mL.
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
939
NCBI Official Name:
CD27 molecule
NCBI Official Symbol:
CD27
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
45.9 kDa
Protein Accession #:
NP_001233
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P26842

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