ProSci

NGL 2 Recombinant Protein

Product Code:
 
PSI-96-523
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-523-0.1mg0.1mg£657.00
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Further Information

Additional Names:
LRRC4, NGL-2, BAG, NAG14
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
Background References:
  • Zhang Q., et al., 2005, FEBS Lett. 579:3674-3682.
  • Wang JR., et al., 2003, Ai Zheng 22 (9): 897?902.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
64101
NCBI Official Name:
leucine rich repeat containing 4
NCBI Official Symbol:
LRRC4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
55.6 kDa
Protein Accession #:
AAI11562.1
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9HBW1

Documents