ProSci

IL 2 R beta Recombinant Protein

Product Code:
 
PSI-96-097
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-097-0.1mg0.1mg£765.00
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Further Information

Additional Names:
IL2RB, RP5-1170K4.6, CD122, P70-75
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Background References:
  • Mulloy J.C., et al., 1996, J. Virol. 70:3599-3605.
  • Lindholm C.K., 2002, Biochem. Biophys. Res. Commun. 296:929-936.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
3560
NCBI Official Name:
interleukin 2 receptor, beta
NCBI Official Symbol:
IL2RB
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
25.4 kDa
Protein Accession #:
NP_000869.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P14784

Documents