ProSci

FABP 2 Recombinant Protein

Product Code:
 
PSI-96-290
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-290-0.2mg0.2mg£626.00
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Further Information

Additional Names:
FABP2, FABPI, I-FABP
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Fatty acid-binding protein 2 (FABP2), is also known as Fatty acid-binding protein, intestinal (FABPI), Intestinal-type fatty acid-binding protein (I-FABP). FABP2 belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. FABP2 / FABPI is expressed in the small intestine and at much lower levels in the large intestine and is highest expressed in the jejunum. FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
Background References:
  • Pelsers M.M.A.L., et al., 2003, Clin. Biochem. 36:529-535.
  • Darimont C., et al., 1999, Am. J. Physiol. 276:G606-G612.
Biological Activity:
The binding affinity of Recombinant Human FABP2/I-FABP for the synthetic ligand cis-parinaric acid has been measured by fluorescence titration. Half-maximal fluorescence of 3 μM Recombinant Human FABP2/I-FABP is achieved with approximately 3 μM cis-paranaric acid.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
2169
NCBI Official Name:
fatty acid binding protein 2, intestinal
NCBI Official Symbol:
FABP2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
16 kDa
Protein Accession #:
NP_000125
Purity:
>98% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P12104

Documents