ProSci

RBP4 Antibody

Product Code:
 
PSI-36-256
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Guinea Pig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-36-256-100ug100ug£524.00
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Further Information

Additional Names:
Retinol Binding Protein 4
Application Note:
ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Background:
Retinol binding protein 4 (RBP4; RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human RBP4.
NCBI Gene ID #:
5950
NCBI Official Name:
retinol binding protein 4, plasma
NCBI Official Symbol:
RBP4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
55743122
Protein GI Number:
NP_006735.2
Research Area:
Obesity
SPECIFICITY:
Recognizes human RBP4. Detects a band of ~22-25kDa by Western blot. Weakly cross-reacts with mouse and rat RBP4.
Swissprot #:
P02753
User NOte:
Optimal dilutions for each application to be determined by the researcher.