ProSci

CARMA1 Antibody

Product Code:
 
PSI-36-321
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunocytochemistry (ICC)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C.
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CodeSizePrice
PSI-36-321-100ug100ug£657.00
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Further Information

Additional Names:
CARD11; Bimp3; Caspase Recruitment Domain-containing Protein 11; CARD-containing MAGUK Protein 1
Application Note:
Western Blot: (1ug/ml).
Background:
CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR)-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
N-terminal human CARMA1 (aa 1-221 containing the CARD domain).
NCBI Gene ID #:
84433
NCBI Official Name:
caspase recruitment domain family, member 11
NCBI Official Symbol:
CARD11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
16507952
Protein GI Number:
NP_115791.2
Research Area:
Cancer,Innate Immunity
SPECIFICITY:
Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.
Swissprot #:
Q9BXL7
User NOte:
Optimal dilutions for each application to be determined by the researcher.