ProSci

FNDC4 Recombinant Protein

Product Code:
 
PSI-90-304
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
  • Canine (dog)
  • Human
  • Monkey
  • Mouse
  • Rat
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-90-304-10ug10ug£469.00
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Further Information

Additional Names:
Fibronectin Type III Domain-containing Protein 4, Fibronectin Type III Repeat-containing Protein 1
Application Note:
This recombinant proteins is for research use only.
Background:
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50% identity and 86% similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
Buffer:
Contains PBS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
Tag Free
NCBI Gene ID #:
64838
NCBI Official Name:
fibronectin type III domain containing 4
NCBI Official Symbol:
FNDC4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
Q9H6D8
Protein GI Number:
74762739
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9NYJ7

Documents