ProSci

Jagged-2 Recombinant Protein

Product Code:
 
PSI-90-167
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-90-167-10ug10ug£505.00
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Further Information

Additional Names:
Protein Jagged-2, hJ2, JAG2
Application Note:
This recombinant proteins is for research use only.
Background:
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
Buffer:
Contains PBS + 0.02 % CHAPS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
3714
NCBI Official Name:
jagged 2
NCBI Official Symbol:
JAG2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
Q9Y219
Protein GI Number:
21704277
Purity:
>90% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q61483

Documents