ProSci

EPO non-lytic Recombinant Protein

Product Code:
 
PSI-90-456
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-456-50ug50ug£657.00
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Further Information

Additional Names:
Erythropoietin, Epoetin
Application Note:
This recombinant proteins is for research use only.
Background:
Erythropoietin is the principal hormone involved in the regulation of erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells and the maintenance of a physiological level of circulating erythrocyte mass. It is a glycoprotein produced primarily by the kidney. The biological effects of EPO are mediated by the erythropoietin receptor (Epo R). Genetic variations in EPO is associated with susceptibility to microvascular complications of diabetes type 2 (MVCD2) (including diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease and diabetic neuropathy). It is used for the treatment of anemia and misused as a performance-enhancing drug in endurance athletes.
Biological Activity:
Measured by the dose-dependant stimulation of human megakaryoblastic leukemia cells.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
2056
NCBI Official Name:
erythropoietin
NCBI Official Symbol:
EPO
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000790
Protein GI Number:
62240997
Purity:
>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
P40933

Documents