ProSci

TACI Recombinant Protein

Product Code:
 
PSI-90-265
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-90-265-50ug50ug£597.00
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Further Information

Additional Names:
TNFRSF 13B, Tumor Necrosis Factor Receptor Superfamily Member 13B, Transmembrane Activator and CAML interactor, CD267
Application Note:
This recombinant proteins is for research use only.
Background:
B-cell activating factor belonging to the TNF family receptor (BAFF-R), B-cell maturation antigen (BCMA), and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) play critical functions in promoting B-cell survival by engaging the ligands a proliferation-inducing ligand (APRIL) and/or BAFF. TACI is predominantly expressed on peripheral blood B cells and interacts with the B cell activating factor (BAFF) of ligands and a proliferation inducing ligand (APRIL), which are expressed by numerous cell types, including dendritic cells, macrophages and neutrophils. TNFRSF13B, the gene, which encodes TACI is mutated in nearly 10% of patients with common variable immune deficiency (CVID), an antibody deficiency syndrome characterized by loss of memory B cells and plasma cells.
Biological Activity:
Inhibits BAFF and APRIL activity.
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water.
Concentration:
1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
23495
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 13B
NCBI Official Symbol:
TNFRSF13B
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
O14836
Protein GI Number:
6912694
Purity:
>90% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O35305

Documents