ProSci

TGF beta 3 Recombinant Protein

Product Code:
 
PSI-92-444
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-92-444-0.05mg0.05mg£838.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Transforming growth factor beta-3, TGFB3, TGF-beta-3, Latency-associated peptide, LAP
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Transforming growth factor beta 3(TGFB3) is a member of a TGF - beta superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- beta RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF- beta 3,mammals develop a deformity known as a cleft palate.
Buffer:
Lyophilized from a 0.2 um filtered solution of 4 mM HCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
Tag Free
NCBI Gene ID #:
7043
NCBI Official Name:
transforming growth factor beta 3
NCBI Official Symbol:
TGFB3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
12.7 kD
Protein Accession #:
P10600
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P10600

Documents