ProSci

IL-6 Recombinant Protein

Product Code:
 
PSI-90-290
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-290-10ug10ug£344.00
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Further Information

Additional Names:
Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
Biological Activity:
Promotes growth of hybridoma/plasma cells at concentration <0.1ng /ml.
Buffer:
Contains PBS. Reconstitute with 100 μl sterile water.
Concentration:
0.1 mg /ml after reconstitution
Fusion Tag:
Fc Tag
NCBI Gene ID #:
16193
NCBI Official Name:
interleukin 6
NCBI Official Symbol:
Il6
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
P08505
Protein GI Number:
124348
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P48023

Documents