ProSci

IL-10 non-lytic Recombinant Protein

Product Code:
 
PSI-90-500
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-500-10ug10ug£524.00
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Further Information

Additional Names:
Interleukin-10, Cytokine Sythesis Inhibitory Factor, CSIF
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
Biological Activity:
6,000 units/ug as determined by ELISA. Bioactivity demonstrated in cytokine synthesis inhibition assay, measuring inhibition of IL-6 production by PU5-1 cells.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
16153
NCBI Official Name:
interleukin 10
NCBI Official Symbol:
Il10
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
AAI37845
Protein GI Number:
187952737
Purity:
>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
Q8VIM0

Documents