ProSci

SOD2 Recombinant Protein

Product Code:
 
PSI-91-566
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-566-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Superoxide Dismutase [Mn] Mitochondrial, SOD2, Mn-SOD
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron disease, and cancer. SOD2 destroys superoxide anion radicals which are usually produced within the cells and which are toxic to biological systems.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris,100mM NaCl,50% glycerol,pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
6648
NCBI Official Name:
superoxide dismutase 2, mitochondrial
NCBI Official Symbol:
SOD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
23.24 kD
Protein Accession #:
P04179
Protein GI Number:
767957252
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P04179

Documents