UBE2K Recombinant Protein
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Ubiquitin-Conjugating Enzyme E2 K, Huntingtin-Interacting Protein 2, HIP-2, Ubiquitin Carrier Protein, Ubiquitin-Conjugating Enzyme E2-25 kDa, Ubiquitin-Conjugating Enzyme E2(25K), Ubiquitin-Conjugating Enzyme E2-25K, Ubiquitin-Protein Ligase, UBE2K, HIP2, LIG, E2-25K
This recombinant protein can be used for biological assays. For research use only.
Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.
Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
N-GST tag
3093
ubiquitin conjugating enzyme E2 K
UBE2K
Homo sapiens
Liquid
Predicted Molecular Weight:
48.7 kD
P61086
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
E. coli
P61086