ProSci

Cathepsin B Recombinant Protein

Product Code:
 
PSI-91-365
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-365-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
1508
NCBI Official Name:
cathepsin B
NCBI Official Symbol:
CTSB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
36.9 kD
Protein Accession #:
P07858
Protein GI Number:
767983919
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P07858

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