ProSci

Grancalcin Recombinant Protein

Product Code:
 
PSI-91-126
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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CodeSizePrice
PSI-91-126-0.05mg0.05mg£657.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Grancalcin, GCA, GCL
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions, which suggested a role for grancalcin in granule-membrane fusion and degranulation.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 500mM Nacl, pH 8.5 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
N-GST tag
NCBI Gene ID #:
25801
NCBI Official Name:
grancalcin
NCBI Official Symbol:
GCA
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
50.3 kD
Protein Accession #:
P28676
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P28676

Documents