ProSci

Ribonuclease 3 Recombinant Protein

Product Code:
 
PSI-91-718
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-718-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Eosinophil Cationic Protein, ECP, Ribonuclease 3, RNase 3, RNASE3, RNS3
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,1mMDTT,10%Glycerol,pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
6037
NCBI Official Name:
ribonuclease A family member 3
NCBI Official Symbol:
RNASE3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
16.6 kD
Protein Accession #:
P12724
Protein GI Number:
189054143
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P12724

Documents