PDI-Associated 1 Recombinant Protein

Product Code:

PSI-92-109

Product Group:

Recombinant Proteins

Supplier:

ProSci

Regulatory Status:

RUO

Target Species:

Human

Storage:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

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Code	Size	Price

PSI-92-109-0.05mg

0.05mg

£613.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Additional Names:

Protein Disulfide-Isomerase, PDI, Cellular Thyroid Hormone-Binding Protein, Prolyl 4-Hydroxylase Subunit Beta, p55, P4HB, ERBA2L, PDIA1, PO4DB

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Protein Disulfide-Isomerase (P4HB) is an endoplasmic reticulum lumen protein that belongs to the protein disulfide isomerase family. P4HB contains two thioredoxin domains and catalyzes the formation, breakage, and rearrangement of -S-S- bonds in proteins. P4HB is involved in hydroxylation of prolyl residues in preprocollagen. P4HB has the ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner. P4HB plays a role in both the influx and efflux of S-nitrosothiol-bound nitric oxide.

Buffer:

Supplied as a 0.2 um filtered solution of PBS, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Fusion Tag:

C-6 His tag

NCBI Gene ID #:

5034

NCBI Official Name:

prolyl 4-hydroxylase subunit beta

NCBI Official Symbol:

P4HB

NCBI Organism:

Homo sapiens

Physical State:

Liquid

Predicted Molecular Weight:

55.9 kD

Protein Accession #:

P07237

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

P07237

Documents

Datasheet