ProSci

Angiopoietin-like protein 8 Recombinant Protein

Product Code:
 
PSI-91-639
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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CodeSizePrice
PSI-91-639-0.05mg0.05mg£838.00
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This product comes from: United States.
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Further Information

Additional Names:
Betatrophin, Angiopoietin-like protein 8, Lipasin, Angptl8
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proliferation is promising in diabetes therapy. Betatrophin treatment could supply or replace insulin injections by increasing the number of insulin-producing cells in diabetes.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
N-Fc tag
NCBI Gene ID #:
55908
NCBI Official Name:
angiopoietin like 8
NCBI Official Symbol:
ANGPTL8
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
48 kD
Protein Accession #:
Q6UXH0
Protein GI Number:
291219911
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q6UXH0

Documents