ProSci

Ephrin Type-B Receptor 1 Recombinant Protein

Product Code:
 
PSI-91-886
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-91-886-0.05mg0.05mg£838.00
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Further Information

Additional Names:
Ephrin Type-B Receptor 1, ELK, EPH Tyrosine Kinase 2, EPH-Kike Kinase 6, EK6, hEK6, Neuronally-Expressed EPH-Related Tyrosine Kinase, NET, Tyrosine-Protein Knase Receptor EPH-2, EPHB1, EPHT2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases involved in the development of embryonic nervous and vascular systems. EPHB1 contains two fibronectin type-III domains, one protein kinase domain and one Sterile Alpha Motif (SAM)domain. EPHB1 is able to stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which is also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to Ephrin-B1, Ephrin-B2 and Ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
C-Fc tag
NCBI Gene ID #:
2047
NCBI Official Name:
EPH receptor B1
NCBI Official Symbol:
EPHB1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
85.5 kD
Protein Accession #:
P54762
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P54762

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