ProSci

KATNB1 Antibody

Product Code:
 
PSI-58-590
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Y79 cell line lysates (35ug/lane).
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Western blot analysis in Y79 cell line lysates (35ug/lane).

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PSI-58-590-400ul400ul£626.00
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Further Information

Additional Names:
Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}, Katanin p80 subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}, p80 katanin {ECO:0000255|HAMAP-Rule:MF_03022}, KATNB1 {ECO:0000255|HAMAP-Rule:MF_03022}
Application Note:
For WB starting dilution is: 1:1000
Background:
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.
Background References:
  • Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
  • Cummings, C.M., et al. J. Biol. Chem. 284(17):11663-11675(2009)
  • Sudo, H., et al. Hum. Mol. Genet. 17(16):2524-2540(2008)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KATNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-359 amino acids from the Central region of human KATNB1.
NCBI Gene ID #:
10300
NCBI Official Name:
Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}
NCBI Official Symbol:
KATNB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q9BVA0
Protein GI Number:
60390213
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9BVA0
User NOte:
Optimal dilutions for each application to be determined by the researcher.